VI ADVANCED UIMP-CSIC SUMMER SCHOOL ON INTEGRATIVE MOLECULAR CELL BIOLOGY
2019 Edition: Constructing a Synthetic Cell
2019 PROGRAM
26-30 August 2019
Universidad Internacional Menéndez Pelayo (UIMP)
La Magdalena Palace, Santander (Spain)
DIRECTORS:
Prof. Germán Rivas. CSIC Research Professor. CIB-CSIC, Madrid
E-mail: grivas@cib.csic.es
Prof. Rafael Giraldo. CSIC Research Professor. CNB-CSIC, Madrid
E-mail: rgiraldo@cnb.csic.es
Morning session
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Opening ceremony
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Protocells (molecular origins of life), minimal cells and artificial cells (I)
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Federico Morán (Dpto. Bioquímica, Facultad de Ciencias Químicas, UCM, Madrid) - Simple models of metabolic closure: Rosen revisited
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Juli Peretó (Instituto de Biología Integrativa y de Sistemas – I2SysBio; CSIC – Univ. Valencia) - Building minimal metabolisms
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Afternoon session
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Protocells (molecular origins of life), minimal cells and artificial cells (II)
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Kepa Ruiz-Mirazo (Inst. Biofísica, CSIC-Univ. Pais Vasco, Bilbao) - On the ‘bottom-up’ construction of protocells and its limitations: some recent in vitro and in silico models
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Round table (I). Bottom-up SynBio – from understanding to improving life
Chair: Germán Rivas (CIB-CSIC, Madrid)
MONDAY 26 August 2019
TUESDAY 27 August 2019
Morning session
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Chemistry and physics of life-like systems (I)
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Javier Montenegro (CIQUS, Univ. Santiago de Compostela)- Synthetic supramolecular strategies for primitive cytoskeleton models
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Felix Campelo (Inst. Ciencias Fotónicas - IFCO, Barcelona) - Membrane mechanics: Mechanisms of membrane curvature generation and remodelling
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Chemistry and physics of life-like systems (II)
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Andrés de la Escosura (Dpto. Química Orgánica, Facultad de Ciencias, UAM, Madrid) - Chemical roots of biological evolution: A theoretical and experimental approach to understand abiogenesis
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Afternoon session
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Workshop (I): In silico synthetic biology
(Computer Facility, UIMP, Campus Los Castros)
- Raúl Fernández (IBBTEC-U. Cantabria/CSIC, Santander)
- Alfonso Rodríguez-Patón (Lab. Inteligencia Artificial, ETS-Informática; UPM, Madrid)
WEDNESDAY 28 August 2019
Morning session
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Mastering biological complexity: towards a new biology? (I)
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Amparo Latorre (Dpto. de Genética, U. Valencia / I2SysBio, CSIC-UV) - Symbionts as natural machines
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Fernando de la Cruz (IBBTEC-U. Cantabria/CSIC, Santander - Bacterial computing by plasmid transmission
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Mastering biological complexity: towards a new biology? (II)
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Thomas Surrey (Francis Crick Inst., London / CRG-Barcelona - Self-organization of microtubules, motors and bundlers
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Afternoon session
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Round table (II). Biology 2.0?
Chair: Rafael Giralddo (CNB-CSIC, Madrid)
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Preparing the next generation of molecular and cell biology scientists: The UIMP-CSIC Master on Molecular and Cellular Integrative Biology (Mcib)
Chairs: Germán Rivas (CIB-CSIC, Madrid) and Rafael Giraldo (CNB-CSIC, Madrid)
Will participate UIMP and CSIC representatives and former Mcib students currently doing their Ph.D. thesis on SynBio-related topics: Adrián Merino (Max Planck Inst. Biochemistry, Martinsried) and Irene Tomico (TU Vienna).
THURSDAY 29 August 2019
Morning session
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Synthetic cells – a European scientific challenge (I)
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Petra Schwille (Max Planck Inst. Biochemistry, Martinsried, Germany) - Minimal machinery to controllably divide a protocell
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Synthetic cells – from academy to industry
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Susana Camarero (CIB-CSIC, Madrid) - Enzyme directed evolution: an awarded and invaluable technology to develop industrial biocatalysts and creative chemistry
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Daniel López (CNB-CSIC, Madrid) - Assembly and diassembly of membrane microdomains in bacteria to fight antibiotic resistant infections.
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Afternoon session
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Workshop (II). Do-it-yourself portable lab: microfluidics in synthetic biology
Begoña Monterroso (CIB-CSIC, Madrid)
Alfonso Rodríguez-Patón (Lab. Inteligencia Artificial, ETS-Informática; UPM. Madrid)
FRIDAY 30 August 2019
Morning session
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Synthetic cells – a European scientific challenge (II)
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Hagan Bayley (Oxford Univ., UK) - Synthetic tissues from communicating droplet networks
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Marileen Dogterom (Technical Univ. Delft, NL) - TBA
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CLOSING LECTURE – Victor de Lorenzo (Dpto. Biología de Sistemas, CNB-CSIC, Madrid) - The elephant in the SynBio room: what we need to face for making bioengineering a reality
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Closing ceremony